Figure 2.
Endogenous n-3 PUFAs differentially regulate the expression of cytokines during Con A-induced liver injury. (A) Serum levels of IFN-γ, TNF-α, IL-6, IL-17A, IL-4, and IL-10 were determined at 0, 6, 12, and 24 h post-Con A administration (n = 5). (B) Relative intrahepatic mRNA expression levels of IFN-γ, TNF-α, IL-6, IL-17A, IL-4, and IL-10 were measured by quantitative RT-PCR analysis at 0, 6, 12, and 24 h post-Con A administration and expressed as a ratio to GAPDH (n = 5). *p < 0.05, **p < 0.01. Data shown represent three independent experiments with similar results.