Table 2.

cSPC Transplantation Studies.

	Oyama et al., 2007	Liang et al., 2010	Noseda et al., 2015
Injury model	Cryoinjury	Coronary artery ligation	Coronary artery ligation
Recipient	Adult male Wistar rats	Adult female C57Bl/6 mice	Adult female C57Bl/6 mice
Donor	Neonatal GFP-transgenic, syngeneic rats	Adult female C57Bl/6 mice	Adult male C57Bl/6 mice
Transplanted cells	300,000 cSPCs	150,000 cSPCs labeled with fluorescent dye	250,000 cSPC clones labeled with lentiviral mOrange
Administration route	Tail-vein injection	Intracardiac injection into border zone	Intracardiac injection into border zone
Functional outcomes	Not assessed	Not assessed	↓ Infarct size
			↓ Remodeling
			↑ Ejection fraction

Three different approaches have used cSPC transplantation to assess the regenerative ability of cSPCs.