Table 1.
Demographic characteristics of orthopedic surgery patients, comparing IV acetaminophen (Ofirmev) recipients to IV opioid monotherapy recipients
| Characteristic | IV opioids (n = 3,11,090) | IV acetaminophen (n = 1,74,805) |
|---|---|---|
| Age (years), mean (SD) | 64.3 (15.6) | 63.6 (14.0) |
| Female, n (%) | 1,79,779 (57.8) | 1,02,864 (58.8) |
| Race, n (%) | ||
| White | 2,38,421 (76.6) | 1,40,748 (80.5) |
| Black | 24,876 (8.0) | 14,591 (8.4) |
| Hispanic | 47,600 (15.3) | 19,362 (11.1) |
| Unknown | 193 (0.1) | 104 (0.1) |
| APR-DRG severity of illness, n (%) | ||
| Minor | 1,36,264 (43.8) | 80,801 (46.2) |
| Moderate | 1,30,231 (41.9) | 77,862 (44.5) |
| Severe | 36,973 (11.9) | 14,462 (8.3) |
| Extreme | 7622 (2.5) | 1680 (1.0) |
| APR-DRG risk of mortality, n (%) | ||
| Minor | 2,17,279 (69.8) | 1,37,283 (78.5) |
| Moderate | 63,080 (20.3) | 28,648 (16.4) |
| Severe | 24,654 (7.9) | 7454 (4.3) |
| Extreme | 6077 (1.9) | 1420 (0.8) |
| Elective surgery, n (%) | 2,10,663 (67.7) | 1,36,318 (78.0) |
| Hospital region, n (%) | ||
| Midwest | 60,685 (19.5) | 27,639 (15.8) |
| Northeast | 70,154 (22.6) | 28,530 (16.3) |
| South | 1,32,013 (42.4) | 1,04,113 (59.6) |
| West | 48,238 (15.5) | 14,523 (8.3) |
| Surgery type, n (%) | ||
| Total knee replacement | 66,725 (21.4) | 64,399 (36.8) |
| Total hip replacement | 40,140 (12.9) | 33,541 (19.2) |
| Knee revision | 5187 (1.7) | 4869 (2.8) |
| Hip revision or partial replacement | 26,672 (8.6) | 9671 (5.5) |
| Fracture | 64,395 (20.7) | 17,928 (10.3) |
| Othera | 1,07,971 (34.7) | 44,397 (25.4) |
APR-DRG all patient refined-diagnosis related group, IV intravenous, SD standard deviation
a Shoulder and spine