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. 2016 Jun 9;46(8):641–675. doi: 10.1080/10408444.2016.1174669

Table 2.

Decreased frequency of MNCL in NTP studies.

NTP TR Carcinogenic in rodents with decreased MNCL (as per Elwell et al. 1996) Splenic toxicity Sex
TR-351 p-Chloroaniline hydrochloride x M&F
TR-222 C.I. Disperse Yellow 3 x M&F
TR-226 C.I. Solvent Yellow 14 x M&F
TR-225 D & C Red 9 x M&F
TR-360 N,N-Dimethylaniline x M&F
TR-266 Monuron x M&F
TR-442 p-Nitrobenzoic acid x M&F
TR-383 1-Amino-2,4-dibromoanthroquinone x M&F
TR-407 C.I. Pigment Red 3 x M&F
TR-337 Nitrofurazone x M&F
TR-448 Isobutyl nitrite x M&F
TR-233 2-Biphenylamine hydrochloride x M&F
TR-205 4,4′-Oxydianiline x M&F
TR-271 HC Blue 1 x M&F
TR-216 11-Aminodecanoic acid   M&F
  Not carcinogenic in rodents with decreased MNCL (as per Elwell et al. 1996)    
TR-211 C.I. Acid Orange 10 x M&F
TR-330 4-Hexylresorcinol x M&F
TR-411 C.I. Pigment Red 23   M&F
TR-240 Propyl gallate   M&F
TR-322 Phenylephrine hydrochoride   M&F
  Decreased MNCL (Post Elwell et al. 1996)    
TR-527 Malachite green   F
TR-527 Leukomalachite green   M&F
TR-494 Anthraquinone   M&F
TR-383 1-Amino-2,4-dibromoanthraquinone   M&F
TR-493 Emodin   M&F
TR-426 Corn oil, safflower oil, tricaprylin   M