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Effects of metal oxide nanoparticle exposures on selected breathing parameters. The tidal volume (VT) values are expressed as minimum average values of 8–10 mice during the 60-min exposure period (a) or as time-response relationship for Al2O3 nanoparticles (b) or ZnO_1 (c). Figure 2d shows the degree of nose irritation quantified by the time of break (TB) elongation.
