Table 2.
Independent factors associated with the log-transformed plasma level of BNP using the ratio of ECW to ICW
| Variables | Univariate analysis |
Multivariate analysis1 |
||
|---|---|---|---|---|
| ß (95% CI) | p value | ß (95% CI) | p value | |
| Age (per 10 years of age) | 0.32 (0.19 to 0.55) | <0.001 | 0.05 (-0.09 to 0.20) | 0.43 |
| Presence of cardiac comorbidities | 0.45 (0.48 to 0.94) | <0.001 | 0.41 (0.46 to 0.83) | <0.001 |
| BMI | −0.46 (−0.22 to −0.12) | <0.001 | −0.19 (−0.11 to −0.03) | <0.001 |
| Pulse pressure (mm Hg) | 0.18 (0.00 to 0.03) | 0.031 | −0.02 (−0.01 to −0.00) | 0.56 |
| eGFRMDRD (ml/min per 1.73 m2) | −0.48 (−0.05 to −0.02) | <0.001 | −0.19 (−0.02 to −0.01) | 0.003 |
| Serum albumin (mg/dl) | −0.44 (-1.56 to −0.76) | <0.001 | −0.13 (−0.70 to 0.03) | 0.07 |
| Total cholesterol (mg/dl) | −0.17 (−0.01 to −0.00) | 0.048 | −0.09 (−0.01 to 0.00) | 0.12 |
| Triglyceride (mg/dl) | −0.29 (−0.01 to −0.00) | <0.001 | −0.06 (−0.00 to 0.00) | 0.09 |
| C-reactive protein (mg/dl) | 0.18 (0.01 to 0.15) | 0.030 | 0.00 (−0.27 to 0.28) | 0.99 |
| Ratio of ECWBIA/ICWBIA (per 0.01) | 0.59 (0.22 to 0.34) | <0.001 | 0.32 (0.09 to 0.23) | <0. 001 |
eGFRMDRD = Estimated glomerular filtration rate by the Modification of Diet in Renal Disease method; β = standardized regression coefficients; CI = confidence interval.
1
Factors associated with the log-transformed plasma level of BNP in univariate analysis (p < 0.10) were entered in the multivariable model.