Table 2.
Baseline cytokine levels summarized by medians [1st, 3rd quartiles]
| Variable | Donor controls | pa | ESRD, no DM at transplantation |
pb | |
|---|---|---|---|---|---|
| no PTDM | PTDM | ||||
| IL-6, pg/ml | 2.6 [2.1,3.4] | <0.01 | 4.7 [3.3,7.2] | 3.9 [2.7,8.8] | 0.78 |
| IL-8, pg/ml | 10.6 [8.5,14.6] | 0.87 | 12.3 [8.0,16.5] | 10 8 [8.4,13 1] | 0.93 |
| Adiponectin, µg/ml | 8.7 [5.4,13 1] | 0.19 | 12 4 [9.4,17 0] | 9.7 [5.5,15.9] | 0.73 |
| HMW adiponectin, µg/ml | 4.12 [2.57,7.21] | 0.35 | 6.69 [3.61,8.76] | 5.15 [2.57,5.66] | 0.46 |
| Adiponectin ratio, %c | 51 3 [47.3,59 2] | 0.62 | 58 9 [42.0,69 0] | 46.7 [30 8,62.9] | 0.87 |
| TNFα, pg/ml | 9.4 [8.3,10.4] | <0.01 | 15.2 [12 4,20.1] | 17 8 [13.3,30 8] | 0.36 |
| CRP, mg/dl | 1.2 [0.5,2.4] | <0.01 | 4.7 [1.5,6.1] | 2.1 [0.8,4.0] | 0.29 |
| MCP-1, pg/ml | 293 [207, 443] | <0.01 | 406 [332, 491] | 447 [350, 625] | 0.72 |
HMW = High-molecular-weight.
a
Two degrees of freedom test for any differences between groups.
b
No PTDM versus PTDM.
c
HMW adiponectin/total adiponectin × 100.