Table 1.

AP and HR in anesthetized rats

	C-NNa	C-HNa	ACRF-NNa	ACRF-HNa	ANOVA effects, p value
	(n = 9)	(n = 10)	(n = 10)	(n = 8)	adenine	NaCl intake	interaction
SAP, mm Hg	138±18	134±11	181±23	206±16	<0.001	n. s.	<0.05
DAP, mm Hg	91±12	91±8	114±8	129±11	<0.001	<0.05	<0.05
PP, mm Hg	48±7	43±5	68±18	77±7	<0.001	n. s.	n. s.
MAP, mm Hg	110±14	108±9	138±12	159±13	<0.001	<0.05	<0.01
HR, beats/min	304±22	286±26	300±21	285±23	n. s.	<0.05	n. s.

Data are derived from clearance experiments on isoflurane-anesthetized animals performed approximately 10-12 weeks after the beginning of the study (see Methods). All animals received chow with a normal (0.6%) NaCl content from the beginning of the study until 2 weeks prior to the clearance experiments, when the animals were randomized to either remain on the same diet (NNa) or be switched to high-NaCl (4%) chow (HNa). Values are means ± SD. Main effects and between-factor interaction from two-factorial ANOVA are presented. HR = Heart rate; n. s. = not significant.