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. Author manuscript; available in PMC: 2016 Sep 13.
Published in final edited form as: J Viral Hepat. 2014 Dec 18;22(9):691–700. doi: 10.1111/jvh.12375

Table 2.

Predictors of sustained virologic response among those treated with boceprevir- or telaprevir-based regimens

Odds ratio univariable 95% CI Odds ratio multivariable 95% CI
Age, for each 10 year increase 0.85 0.76, 0.95 0.94 0.83, 1.07
Sex, male vs female 1.04 0.7, 1.56 1.03 0.66, 1.61
Race/ethnicity
 White 1
 Black 0.67 0.56, 0.8 0.72 0.59, 0.87
 Hispanic 1.24 0.78, 1.96 1.3 0.78, 2.15
 Other 1.13 0.89, 1.43 1.19 0.92, 1.54
Body mass index, each one unit 0.99 0.97, 1.004 0.99 0.96, 1.01
 increase in kg/m2
Body mass index
 <30 vs ≥30 kg/m2 1.1 0.94, 1.29 1.05 0.79, 1.39
Cirrhosis 0.54 0.45, 0.65 0.42 0.34, 0.53
Treatment experienced Ms treatment 0.66 0.56, 0.78 0.76 0.63, 0.91
 naive
Completed full course of treatment 2.63 2.24, 3.08 2.52 2.12, 3.00
HCV RNA, log IU/mL 0.91 0.88, 0.94 0.91 0.87, 0.94
Baseline alanine aminotransferase 1.002 1.001, 1.004 1.004 1.002, 1.01
 level, U/L
Presence of diabetes 0.78 0.64, 0.95 0.89 0.72, 1.11
ESA use 0.93 0.78, 1.1 0.85 0.70, 1.03
Use of statins 1.18 0.92, 1.5 1.29 0.99, 1.70
Anaemia at baseline 0.56 0.41, 0.78 0.75 0.52, 1.07
Anaemia on treatment 2.04 1.49, 2.78 1.95 1.34, 2.83
Genotype (1a is the comparator group)
 1b 1 0.81, 1.24 1.06 0.85, 1.33
 Not specified 1.1 0.85, 1.41 1.14 0.87, 1.49
BOC vs TPV (TPV is the 1.04 0.84, 1.29 0.82 0.65, 1.05
 comparator group)

BOC, boceprevir-containing regimen; TPV, telaprevir-containing regimen; ESA, erythropoiesis-stimulating agent.