. 2016 Sep 13;9(1):70. doi: 10.1186/s13039-016-0280-6

Table 2.

FA-D2 patients’ karyotypes and molecular cytogenetic findings

	FA-D2 patient	Age (years)	Karyotype	Most frequent breakpoints	Fragile site (FS)	Breakpoint frequency (%)	Telomere fusion frequency (%)	Average telomere length (RTLU^a ± SD)	Radial figures frequency (%)
Group A	1	8	46,XX	1q42.2	distal to FRA1H	1.72	1.95	14.76 ± 3.23	7.06
				14q24.3	FRA14G	3.09
				18q21.3	FRA18B	1.72
	2	6	46,XX	2q35	FRA2U	2.4	1.54	23.02 ± 12.73	1.78
				3p14.2	FRA3B	2.4
				5q33.2	FRA5O	2
				7q32.3	FRA7H	1.6
	3	17	46,XX	3q27.1	FRA3C	2.75	1.62	35.72 ± 7.00	1.88
				5q13.2	FRA5K	2.75
				5q33.2	FRA5O	3.29
Group B	4	3	46,XX	3p14.2	FRA3B	11.07	0.08	20.48 ± 12.24	0.78
				3p21.31	FRA3H	3.95
				7q32.3	FRA7H	1.19
	5	3	46,XX,der(21)t(15;21)(q15;p11.1)[5]/46,XX [15]	1p13	FRA1N	1.76	0.72	21.01 ± 10.33	0.715
				1q21	FRA1F	1.32
				3p21.31	FRA3H	1.32
				11q13	FRA11H	0.88
	6	11	46, XY, der(16)t(1;16)(q42;p11.2)del(1) (q42)[1]/46,XY[31]	3p14.2	FRA3B	1.88	0.23	23.91 ± 6.92	0.23
				3p21.31	FRA3H	0.63
				16q22.1	FRA16C	1.88
				16q23	FRA16D	6.88

^aRTLU–relative telomere length units