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. 2016 Sep 13;15(1):466. doi: 10.1186/s12936-016-1509-x

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The influence of chloroquine and quinine on the CYP2D6-mediated depletion of racemic PQ (a) and its enantiomers (b, c); and formation of 2-hydroxyprimaquine from racemic PQ (d) and e, f over 2 h of incubation. Each point represents values: mean ± S.D. (n = 4)