Table 1.
Under-expressed NQO1 | ||||
---|---|---|---|---|
Cancer type | Gene rank (%) | p value | Fold change | Reference |
ALL | Top 1 | 8.27E−5 | −1.138 | Kirschner-Schwabe [45] |
CML | Top 5 | 1.29E−10 | −1.619 | Radich [46] |
The mRNA expression levels of NQO1 were compared in normal vs different clinical sub-types of leukemia patients using the reported gene ranks, p values, and fold changes. The clinical specimen fold-change is defined as change in NQO1 mRNA expression level in the leukemia tissue compared to NQO1 mRNA expression level in corresponding normal tissue. Gene rank orders are generated based on the p values obtained in differential gene expression analysis. The gene expression data retrieved from the Oncomine compendium is log transformed and the standard deviation was normalized to one