Table 2.
Comparison of NQO1 expression in HL-60 across 6 analyses using human cancer cell lines
| Under-expressed NQO1 | ||||
|---|---|---|---|---|
| Cell line | Gene rank (%) | p value | Fold change | Reference |
| HL-60 | Top 1 | 1.76E−98 | −3.978 | Garnett [48] |
| HL-60 | Top 2 | 1.08E−4 | −7.291 | Compendia (not published) |
| HL-60 | Top 2 | 1.09E−4 | −7.395 | Shankavaram [49] |
| HL-60 | Top 2 | 1.73E−62 | −11.959 | Barretina [47] |
| HL-60 | Top 2 | 1.47E−17 | −4.235 | Wooster (not published) |
| HL-60 | Top 4 | 8.21E−5 | −6.637 | Lee [50] |
The mRNA expression levels of NQO1 in the HL-60 cell line were investigated. The fold-change is defined as decrease in level of NQO1 mRNA expression in the HL-60 or in different leukemia cells compared to expression levels in non-leukemic cell lines. Gene rank orders are generated based on the p values obtained in differential gene expression analysis. The gene expression data retrieved from the oncomine compendium are log transformed and the standard deviation were normalized to one