Table 2.
Target identity of the SCI-related antibody responses
| Clone | Translated cDNA product | Size (amino acids) | Homology on protein level |
|---|---|---|---|
| Coding | |||
| UH.SCI.2 | TEEDDYDVMQDPEFLQSVLENLPGVDPNNEAIRNAMGSLASQATKDGKKDKKEEDKK* | 57 | (56/56) 26S proteasome non-ATPase regulatory subunit 4 (PSMD4) |
| UH.SCI.5 | HRVVDLMAHMASKE* | 14 | (13/13) glyceraldehyde-3-phosphate dehydrogenase (GAPDH) |
| UH.SCI.6 | TFPEGAGPYVDLDEAGGSTGLLMDLAANEKAVHADFFNDFEDLFDDDDIQ* | 50 | (49/50) myeloma-overexpressed gene 2 protein (MYEOV2) |
| UH.SCI.7 | HEFFEHE* | 7 | (7/7) protein S100-B (S100B) |
| UH.SCI.19 | PVETYTVNFGDF* | 12 | (11/11) adipocyte enhancer-binding protein 1 (AEBP1) |
| Non-coding | |||
| UH.SCI.1 | IKTVTSQ* | 7 | (6/7) transmembrane protein 236 (TMEM236) |
| UH.SCI.3 | TNNFITSNKN* | 10 | (6/6) calcium-activated chloride channel regulator 2 (CLCA2) |
| UH.SCI.4 | PLKDIIDNI* | 9 | (6/6) Di-N-acetylchitobiase precursor (CTBS) (6/8) poly(A)-specific ribonuclease PARN (PARN) (6/6) TBC1 domain family member 2B (TBC1D2B) |
| UH.SCI.8 | NSSKTYVGTSDKVQTPSRDLGCPLGSHCSLSLLT* | 34 | No significant similarity found |
| UH.SCI.9 | NSELLSNKSALHKFIKYAFWI* | 21 | (12/19) E3 ubiquitin-protein ligase HACE1 (HACE1) |
| UH.SCI.10 | PFFTVPIPRPGA* | 12 | (8/8) F-box only protein 42 (FBXO42) |
| UH.SCI.11 | EFFDNSRKVDD* | 11 | (6/8) Ras/Rap GTPase-activating protein SynGAP (SYNGAP1) |
| UH.SCI.12 | NSKHSLKS* | 8 | (6/7) zinc finger protein 148 (ZNF148) |
| UH.SCI.13 | EDKT* | 4 | (4/4) Tax1-binding protein 3 (TAX1BP3) |
| UH.SCI.14 | TQEGAGSERGVITTF* | 15 | (10/14) receptor-type tyrosine-protein phosphatase eta (PTPRJ) |
| UH.SCI.15 | TEGKEQERSDKDE* | 13 | (7/9) Espin (ESPN) |
| UH.SCI.16 | QGEDKISVY* | 9 | (6/6) Midasin (MDN1) |
| UH.SCI.17 | NSLHSLLGQKNND* | 13 | (10/13) Zinc finger protein 28 (ZNF28) |
| UH.SCI.18 | QRLFRQSSSQELLGCGSKTLMGGEGWLLEEGRSQTGQTVLLTPSPAQRALPLWPLLQTPALTHTPLGLHSFALKDLPKSPFPCLASPLRRERYLQNWVGGMSMNCPSIWDMLHQSERENK | 120 | No significant similarity found |
*stop codon