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. 2016 Sep 13;35(1):140. doi: 10.1186/s13046-016-0413-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — The inhibition of p-IRAK1 attenuated proliferation in HCC cells. a The protein levels of p-IRAK1 and total IRAK1 in SMMU-7721 and HepG2 with IRAK1/4 inhibitors (0, 10 μM, 20 μM). b Cell migration analysis in SMMU-7721 cell lines with IRAK1/4 inhibitors (0, 20 μM) treatment for 24 h. c The proliferation analysis in four different cell lines with IRAK1/4 inhibitors (0, 10 μM, 20 μM) for 1–5 days. d Colony formation analysis in SMMU-7721 and HepG2 cells with IRAK1/4 inhibitor (0, 10 μM and 20 μM) for 48 h