Table 5.

Quality of evidence

Quality rating	Criteria
High	Consistent findings in multiple studies of at least good quality OR one study of excellent quality AND a total sample size of ≥100 patients
Moderate	Conflicting findings in multiple studies of at least good quality OR consistent findings in multiple studies of at least fair quality OR one study of good quality AND a total sample size of ≥50 patients
Low	Conflicting findings in multiple studies of at least fair quality OR one study of fair quality AND a total sample size of ≥30 patients
Very low	Only studies of poor quality OR a total sample size of <30 patients
Unknown	No studies