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. 2016 Jun 8;20(10):1872–1888. doi: 10.1111/jcmm.12877

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© 2016 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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I‐V curves of maximal currents. (A and B) Ca_V2.1, (C and D) Ca_V2.2, (E and F) Ca_V2.2_+γ2 channels. (A, C and E) I‐V curve of a single oocyte. (B, D and F) Pooled data from 7–9 (B), 9–12 (D) and 7–10 (F) oocytes exposed to 0.5–5.0 MPa pressure (colour indicated), normalized to maximal current at 0.1 MPa, holding potential is adjusted [ΔV (mV)] so that 0 indicates the potential at which maximal current is obtained (V_Imax). Statistical significance for each point on the curve is indicated by corresponding colour asterisks (P < 0.05). Dec indicates decompression.