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General qualitative effect of HP on measured channel characteristics
| Imax | Conductance | Inactivation | TTP | τRise | τDecay Fast | τDecay Slow | τTail | |
|---|---|---|---|---|---|---|---|---|
| CaV2.1 | = | = | = | = | = | = | = | ↑(=) |
| CaV2.2 | ↑ | ↑ | ↑(↓) | ↓/↑/= | =/↑/(=) | ↓ | ↓ | ↑ |
| CaV2.2+γ2 | ↑ | ↑ | ↓ | ↑ | = | ↑ | ↑ | ↑ |
↑, increase; ↓, decrease; =, no change; ( ), stronger depolarization; /, higher HP.
