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Proportion of cells with activated histone H2AX in STAT1+/+ and STAT−/− cells following MNNG exposure
| Percentage of S139‐H2AX‐positive cells/total cells | Number of foci per cell | |||
|---|---|---|---|---|
| STAT1+/+ | STAT1−/− | STAT1+/+ | STAT1−/− | |
| Untreated | 30 | 38 | 9 | 10 |
| MNNG (10 μM, 72 hrs) | 49 | 96a | 25 | 55 |
Among which 50% exhibiting a very strong staining. S139‐H2AX‐positive cells were numbered relative to a minimum of 80 cells. Numbers of foci per cell were evaluated under similar conditions.
