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. 2016 Jul 22;20(10):1803–1812. doi: 10.1111/jcmm.12865

Figure 6.

Figure 6

Effect of LNT on the level of nuclear NF‐κB and Pdx‐1 in STZ‐treated INS‐1 cells. (A) Following pre‐incubation with LNT for 30 min., the cells were treated with the indicated concentrations of LNT and STZ (0.5 mM) for 24 hrs. Nuclear NF‐κB p65 was determined by immunoblotting. (B) Quantification of NF‐κB p65 protein level is shown as in A. (C) INS‐1 cells were treated as in A, and the protein level of Pdx‐1 was determined by Western blot analysis. (D) Quantification of NF‐κB p65 protein level is shown as in C. **P < 0.01 compared with untreated control group; # P < 0.05 compared to the STZ group.