. Author manuscript; available in PMC: 2017 Aug 15.

Published in final edited form as: Chem Res Toxicol. 2016 Jul 20;29(8):1335–1344. doi: 10.1021/acs.chemrestox.6b00146

Table 3.

Number of 1,N²-εdG Adducts/10⁸ dG, M₁dG Adducts/10⁸ dG, CrdG Adducts/10⁸ dG, HNEdG Adducts/10⁸ dG, and AcrdG Adducts/10⁸ dG Measured in Sprague-Dawley Rat Hepatic DNA Following Exposure to PCB 126 (1000 ng/kg/day) or the Binary Mixture of PCB 126 + PCB 153 (1000 ng/kg/day + 1000 μg/kg/day) for 53 weeks

	PCB 126 add/10⁸ dG	binary add/10⁸ dG
1,N²-εdG control	2.26 ± 0.15	2.59 ± 0.36
1,N²-εdG exposed	2.74 ± 0.43	4.19 ± 0.98^b
M₁dG control	4.02 ± 0.73	3.03 ± 0.48
M₁dG exposed^a	5.65 ± 1.86^b	5.80 ± 1.65
CrdG control	0.60 ± 0.14	0.34 ± 0.06
CrdG exposed^a	0.68 ± 0.18	0.66 ± 0.20
HNEdG control	1.01 ± 0.11	0.93 ± 0.36
HNEdG exposed^a	1.17 ± 0.25	2.27 ± 1.66
AcrdG control	9.32 ± 0.74	12.70 ± 2.93
AcrdG exposed^a	11.90 ± 1.91^c	24.30 ± 4.03^b

Indicates exposure to PCB 126 (1000 ng/kg/day) and binary (PCB 126 + 153) (1000 ng/kg/day + 1000 μg/kg/day) for 53 wks.

Indicates p ≤ 0.05.

Indicates p ≤ 0.01.