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. 2016 Sep 8;4(1):e000260. doi: 10.1136/bmjdrc-2016-000260

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Pg and Ec LPS induced levels of soluble mediators from in cultures of individuals with and without T2D with periodontitis. LPS stimulated cultures from individuals with T2D presented with higher levels of IL-6, IL-8, IL-10, MIP1α, and MIP1β, while those from NT2D individuals showed higher values of GM-CSF. *p<0.05, **p<0.01, ***p<0.001, between T2D and NT2D groups by Mann-Whitney test. Ec LPS, Escherichia coli lipopolysaccharide; GM-CSF, granulocyte-macrophage colony-stimulating factor; IL, interleukin; MIP1, macrophage inflammatory protein 1; NT2D, non-type 2 diabetes; T2D, type 2 diabetes.