Table 2.
p Values for each interaction between the continuous baseline predictor and PEEP intervention for each outcome in the three included trials
Trial/predictor | 60 days mortality | Time to death | Time to unassisted breathing |
---|---|---|---|
LOVS | |||
BMI | 0.7331 | 0.3537 | 0.7507 |
Estimated RC | 0.1078 | 0.0957 | 0.3264 |
PaO2/FiO2 | 0.1247 | 0.0296 | 0.0325 |
Oxygenation index | 0.4337 | 0.1259 | 0.2594 |
EXPRESS | |||
BMI | 0.6989 | 0.7091 | 0.7294 |
Estimated RC | 0.6922 | 0.7053 | 0.4629 |
PaO2/FiO2 | 0.5511 | 0.6095 | 0.7587 |
Oxygenation index | 0.3287 | 0.3041 | 0.9492 |
ALVEOLI | |||
BMI | 0.1844 | 0.0894 | 0.8589 |
Estimated RC | 0.5438 | 0.7938 | 0.1192 |
PaO2/FiO2 | 0.9785 | 0.7647 | 0.2002 |
Oxygenation index | 0.7908 | 0.8835 | 0.8046 |
BMI, body mass index; FiO2, fraction of inspired oxygen; PaO2, arterial partial oxygen pressure (mm Hg); PEEP, positive end-expiratory pressure; RC, respiratory compliance (tidal volume in mL/inspiratory plateau pressure−PEEP in mm Hg).