Figure 6.
S100 protein expression in L4–6 spinal cord segments 1, 2, 4, and 8 weeks after curcumin administration.
(A) Western blot assay results for the S100 protein; (B) grayscale ratio of S100/GAPDH protein. S100 protein levels peak 2 weeks after curcumin administration in each curcumin group and are dose-dependent for each time period. Data are expressed as the mean ± SD (n = 5). One-way analysis of variance and Dunnett's test were used to analyze the difference among groups. *P < 0.05, vs. model group; #P < 0.05, vs. low-dose curcumin group. High-, moderate-, low-dose curcumin groups: curcumin 40, 20, 10 mg/kg/d, respectively. GAPDH: Glyceraldehyde-3-phosphate dehydrogenase.