Table 2.
Study | Depression |
Anxiety |
PTSD |
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Instrument | No.* | Mean (SD) | MH† | MCS | Instrument | Mean (SD) | MH† | MCS | Instrument | Mean (SD) | MH† | MCS | |
6 mo | |||||||||||||
Pooled‡ | HADS-D | ≥763 | 5.7 (5) | −0.74§ | −0.72§ | HADS-A | 6.7 (5) | −0.79§ | −0.75§ | IES-R | 1.0 (0.9) | −0.60§ | −0.62§ |
ALTOS | HADS-D | ≥603 | 6.1 (5) | −0.77 | −0.74 | HADS-A | 7.1 (5) | −0.79 | −0.77 | IES-R | 1.0 (0.9) | −0.63 | −0.65 |
ICAP | HADS-D | ≥160 | 5.4 (4) | −0.65 | −0.64 | HADS-A | 5.6 (5) | −0.75 | −0.70 | IES-R | 0.8 (0.8) | −0.46 | −0.49 |
CESAR | HADS-D | 74 | 4.9 (4) | −0.62 | — | HADS-A | 4.9 (4) | −0.66 | — | — | — | — | — |
PRaCTICAL | HADS-D | ≥212 | 5.3 (4) | −0.72 | −0.72 | HADS-A | 6.5 (5) | −0.81 | −0.73 | DTS | 31.2 (31) | −0.75 | −0.71 |
Elliot | DASS | 159 | 7.8 (8) | −0.75 | −0.73 | DASS | 6.3 (7) | −0.57 | −0.53 | IES | 14.4 (16) | −0.54 | −0.50 |
12 mo | |||||||||||||
Pooled‡ | HADS-D | ≥708 | 5.6 (5) | −0.75§ | −0.75§ | HADS-A | 6.7 (5) | −0.80§ | −0.7§ | IES-R | 1.0 (0.9) | −0.61§ | −0.62§ |
ALTOS | HADS-D | ≥567 | 5.9 (5) | −0.76 | −0.75 | HADS-A | 7.0 (5) | −0.80 | −0.78 | IES-R | 1.0 (0.9) | −0.63 | −0.65 |
ICAP | HADS-D | ≥141 | 5.2 (4) | −0.72 | −0.70 | HADS-A | 6.4 (5) | −0.78 | −0.76 | IES-R | 0.9 (0.9) | −0.52 | −0.51 |
PRaCTICAL | HADS-D | ≥187 | 4.8 (4) | −0.74 | −0.78 | HADS-A | 6.0 (5) | −0.80 | −0.77 | DTS | 26.7 (28) | −0.77 | −0.75 |
Definition of abbreviations: ALTOS = ARDSNet Long Term Outcomes study; CESAR = conventional ventilatory support versus extracorporeal membrane oxygenation for severe adult respiratory failure; DASS = Depression Anxiety Stress Scales; DTS = Davidson Trauma Scale; HADS = Hospital Anxiety and Depression Scale; ICAP = Improving Care of Acute Lung Injury Patients study; IES = Impact of Event Scale; IES-R = Impact of Event Scale-Revised; MCS = SF-36 mental component summary score; MH = SF-36 mental health domain score; PRaCTICAL = a pragmatic randomized, controlled trial of intensive care follow-up programs in improving longer-term outcomes from critical illness; PTSD = post-traumatic stress disorder.
Sample size may vary across analyses because not all participants have all measures; hence, the minimum sample size across all analyzes is presented in each row.
Presented as a normalized score (mean, 50; SD, 10).
Pooled data include ALTOS, ICAP, CESAR, and PRaCTICAL for depression and anxiety, and ALTOS and ICAP for PTSD.
P value ≤ 0.01.