Figure 2.

Receiver operating characteristic curves for the criteria-defined clinical features. The unweighted receiver operating characteristic curve (solid curved line) uses a uniform weight for each of the four significant criteria-defined clinical features. For the weighted curve (dashed line), each clinical feature is weighted by its logistic regression parameter estimate from Table 3 (2.05 for laterality defect, 1.89 for neonatal respiratory distress, 1.28 for nasal congestion, 1.13 for chronic cough and 0.01 for multiple ear infections). The areas under the curve were 0.86 (95% confidence interval, 0.82–0.89) for the weighted receiver operating characteristic curve and 0.84 (95% confidence interval, 0.81–0.88) for the unweighted receiver operating characteristic curve. The weighted curve was minimally better than the unweighted curve (P = 0.019), but the shape was similar except for the region of sensitivity (50–80%).