Table 1.
PCD (n = 205) | Other/Undefined (n = 187) | P Value | |
---|---|---|---|
Female sex | 99 (48%) | 86 (46%) | 0.686 |
Race, white | 171 (83%) | 168 (90%) | 0.076 |
Ethnicity, non-Hispanic | 179 (87%) | 168 (90%) | 0.526 |
Age | |||
Median (range), yr | 8 (0–18) | 7 (0–18) | 0.191 |
Mean ± SD, yr | 7.8 ± 5.4 | 7.0 ± 4.5 | 0.127 |
≤5 yr, n (%) | 75 (37%) | 76 (41%) | 0.467 |
Nasal nitric oxide* | |||
Mean ± SD, nl/min | 20.9 ± 21.8 (n = 121) | 258.3 ± 146.9 (n = 102) | <0.0001 |
Below cutoff of 77 nl/min† | 117 (97%) | 1 (0.9%) | <0.0001 |
Definition of abbreviation: PCD = primary ciliary dyskinesia.
Limited to participants older than 5 years of age who were able to cooperate with the maneuver.
Prior studies established a cutoff of 77 nl/min with sensitivity of 98% for PCD (16).