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. 2016 Aug;13(8):1305–1313. doi: 10.1513/AnnalsATS.201511-748OC

Table 3.

Prevalence of general clinical features and criteria-defined clinical features among participants with primary ciliary dyskinesia versus other/undefined groups and multiple logistic regression model for criteria-defined clinical features

Features Group    
General clinical features PCD (n = 205) Other/Undefined (n = 187) Adjusted Odds Ratio (95% Confidence Interval)* P Value
 Neonatal respiratory distress 166 (81%) 59 (32%) 7.8 (4.6–13.4) <0.0001
 Chronic cough 198 (97%) 155 (83%) 2.4 (0.8–6.7) 0.103
 Chronic nasal congestion 198 (97%) 151 (81%) 6.2 (2.3–16.9) 0.0004
 Situs inversus totalis 95 (46%) 15 (8%) 12.0 (5.6–25.5) <0.0001
 Recurrent otitis 180 (88%) 152 (81%) 1.5 (0.7–3.2) 0.246
Criteria-defined clinical features (see definitions in Figure 1) PCD (n = 204) Other/Undefined (n = 185) Adjusted Odds Ratio (95% Confidence Interval)* P Value
 Unexplained neonatal respiratory distress (feature 1) 116 (57%) 21 (11%) 6.6 (3.5–12.3) <0.0001
 Early-onset, year-round wet cough (feature 2) 128 (62%) 48 (26%) 3.1 (1.7–5.5) 0.0001
 Early-onset, year-round nasal congestion (feature 3) 151 (74%) 74 (40%) 3.4 (1.9–6.3) <0.0001
 Laterality defect (feature 4) 109 (53%) 28 (15%) 7.7 (4.0–14.9) <0.0001
 Multiple ear infections in first 2 yr of life with sequelae 89 (43%) 66 (35%) 1.0 (0.6–1.8) 0.981

Definition of abbreviation: PCD = primary ciliary dyskinesia.

*

Age was adjusted in the model.

One participant with PCD was missing data for the criteria.

Two other/undefined participants were missing data for the criteria.