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. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Diabetes Obes Metab. 2016 Sep;18(Suppl 1):78–86. doi: 10.1111/dom.12729

Figure 5. Overview of β-cell metabolism and glucose-stimulated insulin secretion under different physiological and pathological conditions.

Figure 5

Arrow thickness indicates rate of metabolism. Abbreviations: GSIS, glucose-stimulated insulin secretion; FA, fatty acid; TCA, tricarboxylic acid; T2D, type 2 diabetes mellitus.