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. Author manuscript; available in PMC: 2016 Sep 13.
Published in final edited form as: Lipids. 2015 Mar 25;50(8):721–734. doi: 10.1007/s11745-015-4007-y

Figure 2.

Figure 2

Sterols used in prior sterol substitution studies. Cholesterol is shown with carbon atoms numbered. Sterols with variations on cholesterol studied have included those with substituents replacing or modifying the 3β OH group (named in parentheses, full structures of sterols not shown) including: cholestene (H), cholesterol formate (formate), chlorocholesterol (Cl), epicholesterol (3α-OH), cholesterol palmitate (palmitate), cholesterol ethyl ether (ethyl), 5-cholesten-3-one (3 keto); oxysterols (full structures not shown) with substituents including: 6 ketocholesterol, 7α-OH cholesterol, 7β-OH cholesterol, 19 ketocholesterol, 22 ketocholesterol, 25-OH cholesterol, 20α-OH cholesterol, 22α-OH cholesterol; alkyl chain variants including: stigmasterol, β-sitosterol, fucosterol, campesterol, desmosterol; ring double bond variants including: 7-dehydrocholesterol, allocholesterol, lathosterol; saturated sterol ring variants including: dihydrocholesterol, coprostanol; and sterols/steroids with multiple differences relative to cholesterol including: epicoprostanol, zymosterol, ergosterol, dehydroergosterol, pregnenolone, lanosterol, 4-cholesten-3-one, androstenol, stigmastanol.