Fig. 4.

Dopamine levels in the dorsal striatum of 2-year-old synuclein knockout mice. Dopamine concentrations (in nanograms per milligram of protein) were normalized to the mean value for wild-type animals (100%). The bar chart shows means ± standard error of the mean data obtained from the number of samples shown at the bottom of the corresponding bar. A statistically significant difference between knockout and wild-type groups is denoted by asterisks (^∗p < 0.05, ^∗∗p < 0.01, Kruskal–Wallis analysis of variance with post hoc Mann–Whitney test) and between α-synuclein and α/β/γ-synuclein knockout groups–by hash (^#p < 0.05).