Table 1. Pharmacological profiles of YHS within G protein coupled receptors (GPCRs).
CNS Target | YHS Activity |
---|---|
Dopamine D1 | 3.129 ± 0.2423 (Antagonism) |
Dopamine D2 | 3.091 ± 0.1893 (Antagonism) |
Serotonin 1A/2A/2C/6 | None |
Adrenergic α1B/α2A/α2B/β1/β2 | None |
Muscarinic Acetylcholine R1 | None |
Histamine R2 | None |
Melatonin R1 | None |
Opioid μ, δ, κ | None |
Opioid receptor-like R | None |
Melanin concentrating hormone R1 | None |
Neurokinin R1 | None |
IC50 (μg/ml) values are presented as mean±S.E.M.