Skip to main content
. 2016 Sep 13;11(9):e0162875. doi: 10.1371/journal.pone.0162875

Table 1. Pharmacological profiles of YHS within G protein coupled receptors (GPCRs).

CNS Target YHS Activity
Dopamine D1 3.129 ± 0.2423 (Antagonism)
Dopamine D2 3.091 ± 0.1893 (Antagonism)
Serotonin 1A/2A/2C/6 None
Adrenergic α1B/α2A/α2B/β1/β2 None
Muscarinic Acetylcholine R1 None
Histamine R2 None
Melatonin R1 None
Opioid μ, δ, κ None
Opioid receptor-like R None
Melanin concentrating hormone R1 None
Neurokinin R1 None

IC50 (μg/ml) values are presented as mean±S.E.M.