Table 1. Data collection and refinement statistics.
DENV2 NS5 C-terminal NLS: Impα and DENV3 NS5 C-terminal NLS: Impα data collection and refinement statistics:
| DENV2C-termNLS: Impα | DENV3C-termNLS: Impα | |
|---|---|---|
| Wavelength (Å) | 0.9537 | 0.9537 |
| Resolution range (Å) | 31.32–2.2 (2.279–2.2) | 31.35–2.1 (2.175–2.1) |
| Space group | P 21 21 21 | P 21 21 21 |
| Unit cell (Å, °) | 79.25 88.96 100.39 90 90 90 | 78.94 89.88 100.37 90 90 90 |
| Measured reflections | 160470 (11571) | 172369 (14223) |
| Unique reflections | 36643 (3080) | 41892 (3446) |
| Multiplicity | 4.4 (3.8) | 4.1(4.1) |
| Completeness (%) | 100 (99) | 99 (100) |
| Mean I/sigma (I) | 23.5 (7.6) | 10.5 (1.9) |
| Wilson B-factor (Å2) | 26.63 | 30.26 |
| R pim | 0.021(0.085) | 0.053(0.455) |
| Reflections used in refinement | 36589 (3555) | 41840 (4172) |
| Reflections used for R-free | 1825 (199) | 2088 (175) |
| R-work | 0.1770 (0.1943) | 0.1825 (0.2659) |
| R-free | 0.2158 (0.2678) | 0.2066 (0.2900) |
| Number of non-hydrogen atoms | 3684 | 3713 |
| macromolecules | 3373 | 3371 |
| Protein residues | 440 | 440 |
| RMS (bonds) (Å) | 0.006 | 0.010 |
| RMS (angles) (°) | 1.02 | 1.34 |
| Ramachandran favored (%) | 99 | 99 |
| Ramachandran allowed (%) | 1.4 | 1.4 |
| Ramachandran outliers (%) | 0 | 0 |
| Rotamer outliers (%) | 2.2 | 2.2 |
| Clashscore | 2.79 | 5.14 |
| Average B-factor (Å2) | 36.08 | 41.38 |
| macromolecules | 35.66 | 40.94 |
| solvent | 40.65 | 45.68 |
Statistics for the highest-resolution shell are shown in parentheses.