Table 3. Comparison of PDB deposited NLSs binding only the Impα2 major site.
Source protein | IMPα2 Major cNLS binding site | PDB code | ||||
---|---|---|---|---|---|---|
P1 | P2 | P3 | P4 | P5 | ||
Dengue 2 NS5 C-terminus | M | K | R | F | R | 5HHG (in this paper) |
Dengue 3 NS5 C-terminus | M | K | R | F | R | 5FC8 (in this paper) |
SV40T | K | K | K | R | K | 1EJL [60], 1BK6 [61], 1Q1S [62], 1Q1T [62] |
Human androgen receptor | R | K | L | K | K | 3BTR [63] |
αIBB | L | K | K | R | N | 1IAL [50], 1IQ1 [64] |
Venezuelan Equine Encephalitis Capsid | A | K | K | P | K | 3VE6 [65] |
Ku70 | S | K | R | P | K | 3RZX [66] |
Ku80 | A | K | K | L | K | 3RZ9 [66] |
CLIC4 | A | K | K | Y | R | 3OQS [67] |