TABLE 1.

Correlations between capture of infectious SIVmac251 and other antibody measurements^a

Parameter	Value for correlation with:
	Avidity	gp130 IgG	V1V2 IgG	E660 gp140 IgG	E660 V1V2 IgG	239 V1V2 IgG	Cyclic V2 IgG	E543 cyclic V2 IgG	Cyclic V2 IgA	Cyclic V2 E543 IgA	E660 gp140 IgA	gp140 IgA	Neutralization		gp130 rectal IgG	Cyclic V2 rectal IgGc	Cyclic V2 sp act	E543 V2 rectal IgGc	E543 V2 rectal IgAc	V2 rectal IgAc	ADCC		Phagocytosis
													SIVmac251-6	SIVmac251 (challenge)							Maximum kill	Titer
Correlation coefficient	0.002	0.50	0.31	0.54	0.17	0.32	0.49	0.59	0.16	0.27	0.53	0.35	0.71	−0.066	0.64	−0.16	−0.33	−0.20	−0.27	−0.22	−0.16	0.52	0.45
P valueb	0.99	0.0004	0.031	0.0001	0.25	0.026	0.0004	<0.0001	0.27 (MW)	0.061 (JT)	<0.0001	0.014	<0.0001	0.65	<0.0001	0.21 (JT)	0.049 (MW)	0.21	0.085 (JT)	0.19 (JT)	0.26	0.0001	0.0013
No. of samples	50	49	49	49	49	49	50	50	50	50	50	50	50	50	39	42	48	42	41	41	50	50	50

^aE543 refers to SIVsmE543. Correlation coefficients and P values are Spearman's unless otherwise indicated.

^bMW, Mann-Whitney test for antibody values of =0 versus >0; JT, Jonckheere-Terpstra test for postvaccination minus prevaccination values of <0 versus =0 versus >0. Significant values (P < 0.05) are in bold; P < 0.004 is significant after correction for multiple comparisons.

^cValues obtained by subtracting prevaccination from postvaccination results.