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Analysis of involvement of VZV kinases in CREB phosphorylation upon infection. Fibroblasts were infected with VZV-pOka, VZV-ORF66G102A, VZV-chimera D, or VZV-ORF47-DN 24 h prior to fixation and staining with mouse anti-gE and rabbit anti-pCREB antibodies and analysis by flow cytometry. Shown are the levels of pCREB in uninfected control cells (shaded), bystanders (dotted lines), and infected cells (solid lines) for the indicated viruses.
