FIG 6.

CAMP activity is located in the LL-37 domain. (A) Schematics of CAMP and its deletion mutant. aa, amino acids. (B) Deletion mutant with an HA tag expressed in BE-KO cells by a lentiviral vector detected by immunoblotting. (C and D) BE-KO cells expressing either ApoE, CAMP, or LL-37 were infected with HCV at a multiplicity of infection of 1, and intracellular HCV RNA levels (C) and infectious titers (D) in the supernatants at 72 h postinfection were determined by qRT-PCR and a focus-forming assay, respectively. In all cases, asterisks indicate significant differences (*, P < 0.05; **, P < 0.01) versus the results for control cells.