Table 2.
Enzymatic activity (U mg−1 P) | Tissue | CTRL | CTRL + HBO2 | DSS | DSS + HBO2 |
---|---|---|---|---|---|
CAT | Colon | 6.77 ± 3.04 | 5.39 ± 1.07 | 4.11 ± 0.33 | 4.23 ± 0.20 |
MLN | 13.90 ± 0.39 | 11.78 ± 1.71 | 9.06 ± 0.22∗ | 12.62 ± 0.42 | |
Spleen | 10.44 ± 1.94 | 14.00 ± 0.97 | 6.75 ± 0.53∗ | 14.28 ± 1.11# | |
| |||||
GPx | Colon | 0.084 ± 0.028 | 0.097 ± 0.012 | 0.080 ± 0.008 | 0.072 ± 0.003 |
MLN | 0.164 ± 0.006 | 0.158 ± 0.021 | 0.175 ± 0.004 | 0.172 ± 0.007 | |
Spleen | 0.098 ± 0.005 | 0.109 ± 0.003 | 0.114 ± 0.007 | 0.134 ± 0.004∗† | |
| |||||
SOD | Colon | 15.40 ± 3.29 | 27.86 ± 3.55∗ | 30.56 ± 2.70∗ | 30.97 ± 1.58∗ |
MLN | 36.53 ± 2.80 | 33.96 ± 3.33 | 34.48 ± 1.62 | 35.30 ± 1.75 | |
Spleen | 19.87 ± 1.15 | 17.91 ± 0.72 | 20.93 ± 1.03 | 25.34 ± 1.61∗† |
BALB/c mice at the age of 10–12 weeks were randomly assigned into 4 groups (n = 5/group): CTRL: control mice, CTRL + HBO2: control mice undergoing HBO2 (60 min/2.4 ATM, 2x/day, days 1–8), DSS: mice receiving DSS (5% w/v, days 1–7), and DSS + HBO2: DSS treated mice undergoing HBO2. Presented data (mean ± s.e.m.) are representative results from one experiment with min. five mice/group; P < 0.05 was considered significant; ∗statistically different from CTRL, P < 0.05; #statistically different from DSS, P < 0.05; †statistically different from CTRL + HBO2, P < 0.05.