Table 4.
Probe Sets With Some of the Most Increased Signals in Sarcoidosis vs Uninflamed Controls for All Tissue Types Studieda
Probe Set | Gene Symbol | Blood
|
Orbit
|
Lacrimal Gland
|
|||
---|---|---|---|---|---|---|---|
Fold Difference | P Value for FDR | Fold Difference | P Value for FDR | Fold Difference | P Value for FDR | ||
214511_x_at | FCGR1B | 4.69 | 0.00 × 100 | 13.44 | 2.27 × 10−4 | 10.75 | 3.75 × 10−5 |
| |||||||
204533_at | CXCL10 | 2.83 | 5.03 × 10−1 | 16.53 | 6.03 × 10−4 | 7.87 | 5.15 × 10−3 |
| |||||||
229390_at | RP1-93H18.5 | 2.38 | 0.00 × 100 | 10.62 | 2.27 × 10−3 | 12.91 | 2.06 × 10−3 |
| |||||||
239196_at | ANKRD22 | 5.57 | 0.00 × 100 | 9.89 | 5.88 × 10−4 | 9.04 | 7.41 × 10−5 |
| |||||||
210029_at | INDO | 3.69 | 0.00 × 100 | 8.11 | 4.72 × 10−3 | 12.11 | 1.44 × 10−4 |
| |||||||
231577_s_at | GBP1 | 2.72 | 0.00 × 100 | 6.53 | 1.80 × 10−2 | 14.19 | 5.92 × 10−5 |
| |||||||
209969_s_at | STAT1 | 2.25 | 0.00 × 100 | 9.46 | 3.28 × 10−4 | 11.71 | 5.74 × 10−5 |
| |||||||
238581_at | GBP5 | 3.69 | 0.00 × 100 | 6.10 | 1.91 × 10−3 | 10.62 | 5.47 × 10−4 |
| |||||||
227458_at | CD274 | 4.63 | 0.00 × 100 | 6.14 | 1.27 × 10−3 | 7.42 | 3.15 × 10−4 |
| |||||||
211003_x_at | TGM2 | 2.68 | 1.19 × 100 | 4.24 | 1.29 × 10−3 | 10.13 | 2.77 × 10−6 |
| |||||||
206513_at | AIM2 | 2.00 | 2.50 × 10−1 | 6.87 | 2.12 × 10−4 | 6.57 | 5.72 × 10−5 |
| |||||||
209734_at | NCKAP1L | 2.14 | 1.19 × 100 | 3.64 | 1.97 × 10−4 | 5.88 | 6.81 × 10−5 |
| |||||||
204858_s_at | ECGF1 | 2.05 | 0.00 × 100 | 3.28 | 9.43 × 10−7 | 5.32 | 3.50 × 10−4 |
| |||||||
235574_at | GBP4 | 2.43 | 1.83 × 10−1 | 2.57 | 7.98 × 10−3 | 4.87 | 8.51 × 10−4 |
| |||||||
1561615_s_at | SLC8A1 | 2.08 | 9.25 × 10−1 | 3.00 | 5.90 × 10−3 | 4.42 | 1.24 × 10−4 |
| |||||||
238327_at | GCLMLOC440836 | 2.31 | 0.00 × 100 | 2.56 | 2.55 × 10−3 | 4.54 | 5.28 × 10−5 |
| |||||||
235643_at | SAMD9L | 2.41 | 0.00 × 100 | 2.19 | 3.08 × 10−2 | 4.41 | 1.96 × 10−4 |
| |||||||
227609_at | EPSTI1 | 3.58 | 0.00 × 100 | 2.28 | 1.99 × 10−2 | 3.11 | 4.04 × 10−3 |
| |||||||
205819_at | MARCO | 2.11 | 1.19 × 100 | 2.08 | 3.98 × 10−4 | 4.76 | 3.50 × 10−4 |
| |||||||
209773_s_at | RRM2 | 2.07 | 2.86 × 100 | 3.30 | 7.17 × 10−5 | 2.22 | 2.51 × 10−2 |
| |||||||
215761_at | DMXL2 | 2.19 | 1.16 × 10−1 | 2.99 | 4.66 × 10−5 | 2.21 | 3.93 × 10−2 |
| |||||||
232610_at | PARP14 | 2.38 | 1.83 × 10−1 | 2.14 | 2.63 × 10−3 | 2.42 | 3.76 × 10−2 |
Abbreviation: FDR, false discovery rate.
Only the probe set with the greatest fold difference for a given gene is reported. Only probe sets with adequate annotation are included. The complete list of probe sets is reported in eTable 5 in the Supplement.