Table 1.

Myosin superfamily members necessary for human hearing

Gene	Myosin	Locus1	MIM	Reference
MYO3A	myosin 3a	DFNB30	607101	Walsh et al., 2002
MYO6	myosin 6	DFNB37/DFNA22	607821/606346	Melchionda et al., 2001; Ahmed et al., 2003
MYO7A	myosin 7a	DFNB2/DFNA11/USH1B	600060/601317/276900	Liu et al., 1997a; Liu et al., 1997b; Weil et al., 1997
MYH9	myosin 9	DFNA17	603622	Lalwani et al., 2000
MYH14	myosin 14	DFNA4	600652	Donaudy et al., 2004
MYO15A	myosin 15	DFNB3	600316	Friedman et al., 1995; Wang et al., 1998

¹DFNA locus mapped in a family segregating nonsyndromic deafness as a dominant trait. A DFNB locus mapped in a family segregating nonsyndromic deafness as a recessive trait. USH1B is a locus for Usher syndrome type 1 (OMIM# 276900). Mutations of MYO7A are associated with DFNA, DFNB or USH.