Table 1.
Comparison of baseline demographic and clinical characteristics among the National Parkinson Foundation Parkinson’s Outcomes Project cohort
| Variable | Men (N=2,938) | Women (N=1,741) |
p- value |
|
|---|---|---|---|---|
| Mean age in years (SD) | 65.5 (9.7) | 66.9 (9.7) | <0.001 | |
| Disease duration in years (SD) | 8.7 (6.0) | 8.9 (6.6) | 0.176 | |
| % Hoehn and Yahr stage (n)a | 1 | 9.7 (285) | 13.6 (236) | |
| 2 | 53.1 (1559) | 45.6 (794) | ||
| 3 | 26.2 (770) | 25.8 (450) | ||
| 4–5 | 5.0 (146) | 7.2 (126) | <0.001 | |
| Mean # of co-morbidities (SD) | 1.7 (1.3) | 1.8 (1.3) | 0.005 | |
| Mean PDQ-39 (SD) | Sum score | 23.1 (14.8) | 25.2 (15.9) | <0.001 |
| Mobility | 11.0 (10.3) | 13.9 (11.5) | <0.001 | |
| ADL | 7.2 (5.5) | 7.0 (6.0) | 0.267 | |
| Emotional | 5.3 (4.5) | 6.5 (4.9) | <0.001 | |
| Stigma | 2.8 (3.2) | 3.1 (3.4) | 0.009 | |
| Social support | 1.2 (1.8) | 1.4 (2.0) | 0.015 | |
| Cognition | 4.2 (3.1) | 4.0 (3.1) | 0.136 | |
| Pain | 3.6 (2.7) | 4.5 (2.9) | <0.001 | |
| Mean # of medications (SD) | 2.3 (1.2) | 2.3 (1.2) | 0.189 | |
| Mean standardized TUG (SD) | −0.2 (1.0) | 0.0 (1.0) | <0.001 | |
| Mean verbal fluency (SD) | 18.6 (6.5) | 18.5 (6.5) | 0.517 | |
|
Mean 5 word delayed recall (SD) |
2.9 (1.4) | 3.3 (1.4) | <0.001 |
a
178 values missing for men and 126 missing for women;
PDQ-39 = Parkinson’s disease questionnaire; ADL = Activities of Daily Living; TUG = timed up and go