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Rhythmicity of core molecular clock genes in human skeletal muscle. Diurnal mRNA expression of the arrhythmic muscle filament gene TTN (A), the core clock genes CLOCK and BMAL1 (B), PER2 and CRY1 (C), measured by RT-QPCR. Data are normalized to the geometric mean of 3 housekeeping genes and presented as mean ± SEM. *p < 0.05 for the effect of time in all depicted genes.
