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. 2016 Jun 14;5(8):669–679. doi: 10.1016/j.molmet.2016.06.004

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© 2016 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Acute effects of leptin and insulin on SF1 neurons segregate to distinct subpopulations of VMH SF1 neurons. (A) Traces demonstrate a neuron that is acutely activated by leptin, but is not affected by insulin. (B) Traces demonstrate a neuron that is not affected by leptin, but is acutely inhibited by insulin. (C) Traces demonstrate a neuron that is not affected by insulin, but is acutely inhibited by leptin. (D) Images show the location of recordings and acute effects of leptin and insulin.