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. 2016 Jun 22;5(8):646–655. doi: 10.1016/j.molmet.2016.06.007

Figure 4.

Figure 4

AMPK is necessary for PLIN3 expression. (A,B) Representative western blots and quantitative analysis of PLIN3, PLIN2 and PLIN5 protein expression from WT quadriceps muscle or muscle over-expressing a kinase-dead AMPKα2 construct (AMPK KD) (n = 11). (C) PLIN3 mRNA levels in wildtype and AMPK KD quadriceps muscle determined by qPCR (n = 11). (D) Representative western blot and quantitative analysis of nuclear FoxO1 protein content in AMPK wildtype and KD quadriceps (n = 9–11). (E) Triglyceride concentration in dissected quadriceps from fed AMPK wildtype and KD mice (n = 11). **p < 0.01, *p < 0.05 effects of genotype (Wildtype vs AMPK KD). Values are means ± SEM.