Fig. 4.

The influence of rivastigmine (0.5 or 1 mg/kg, i.p.) on the spatial memory impairments caused by acute ethanol (1.75 g/kg, i.p.) administration measured during the Barnes maze task in rats. Fifty minutes prior the probe trial, rats received rivastigmine followed by ethanol (1.75 g/kg) or saline 20 min later (30 min before the probe trial). Escape latency (panels a, c) and number of errors (panels b, d) measured at the probe trial and reversal learning are shown as mean ± SEM of the three trials (n = 12 group). **P < 0.01; ***P < 0.001 vs. saline-treated rats; ^{^^^} P < 0.001 vs. ethanol-treated rats. RV rivastigmine