. 2016 Aug 28;233(19):3473–3501. doi: 10.1007/s00213-016-4396-5

Table 7.

5-HT-ergic vesicular monoamine transporter (VMAT) animal studies

Technique used	Author	Nr pts/controls	Details animals	Dosage drugs	Outcome		Effect size
[¹¹C]DTBZ PET	Fantegrossi et al. (2004)	SA-MDMA 4 PD-Controls 3	Rhesus monkeys	Extensive drug self-administration including opioids and psychostimulants MDMA 1190–2508 mg PD-Controls: MDMA and METH-naive	SA-MDMA vs PD-Controls:
[¹¹C]DTBZ PET	Fantegrossi et al. (2004)	SA-MDMA 4 PD-Controls 3	Rhesus monkeys		DVR midline structures (thalamic and hypothalamic nuclei) vs occipital cortex: no significant differences^a		^b

This table reports the results of the animal studies included on 5-HT-ergic VMAT. “SA-MDMA” is monkeys that self-administered MDMA. “PD-Controls” are polydrug controls (excluding MDMA self-administration). “DVR” is the distribution volume ratio of [¹¹C]DTBZ

^aAlso presented in Table 11: DA-ergic VMAT

^bNot all results were shown in the paper; therefore, the effect sizes could not be calculated