| The methodology described allows the simultaneous analysis of c.460G>A, c.719A>G and c.238G>C changes of the TPMT as well as c.94C>A of the ITPA gene by quick and economic multiplex HRMA. |
| The multiplex HRMA can be used as a sensitive and efficient alternative diagnostic method for the determination of TPMT*2, TPMT*3 and ITPA c.94C>A alleles. |
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