TABLE 1.
Demographic and disease characteristics of the patients at pre-treatment.
| Radical prostatectomy | Radiotherapy | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
|
| ||||||||||
| Variable, n (%) | Norway | USA | Spain | p-value | Total | Norway | USA | Spain | p-value | Total |
| (n=627) | (n=603) | (n=123) | (n=1353) | (n=126) | (n=293) | (n=126) | (n=555) | |||
| Age, median (range) | 64 (44–78) | 60 (39–80) | 65 (45–75) | <0.00113 | 62 (39–80) | 67 (51–78) | 69 (46–85) | 70 (55–83) | ≤0.00812 | 69 (46–85) |
| <65yrs | 382 (61) | 460 (76) | 64 (52) | <0.00113 | 906 (67) | 41 (33) | 86 (29) | 25 (19) | 0.0092 | 152 (27) |
| No comorbid condition | 450 (72) | 513 (85) | 77 (63) | <0.00113 | 1040 (77) | 64 (51) | 200 (67) | 77 (57) | <0.0011 | 341 (62) |
| Paired relationship | 584 (93) | 523 (87) | 109 (87) | <0.0011 | 1216 (90) | 102 (83) | 227 (78) | 118 (87) | 0.0183 | 447 (81) |
| Education above high school level, | 322 (52) | 511 (85) | 8 (7) | <0.001123 | 841 (62) | 57 (46) | 211 (72) | 16 (12) | <0.001123 | 284 (52) |
| PSA (ng/ml), | ||||||||||
| Median (Range) | 8.2 (1.6–75) | 5.5 (0.5–72) | 7.4 (4–23) | ≤0.002123 | 6.9 (0.5–75) | 9.8 (3–87) | 6.3 (0.5–99) | 7.6 (1.2–38) | ≤0.009123 | 7.6 (0.5–99) |
| PSA group | <0.0011 | <0.00112 | ||||||||
| ≤10.0 | 434 (69) | 525 (87) | 99 (81) | 1058 (78) | 66 (52) | 226 (77) | 114 (84) | 406 (73) | ||
| >10–20 | 162 (26) | 65 (11) | 45 (15) | 250 (18) | 38 (30) | 45 (15) | 15 (11) | 98 (18) | ||
| >20 | 31 (5) | 13 (2) | 1 (1) | 45 (3) | 22 (18) | 22 (8) | 7 (5) | 51 (9) | ||
| cT category | <0.0011 | 0.00512 | ||||||||
| T1 | 393 (63) | 437 (73) | 82 (67) | 912 (67) | 53 (42) | 203 (69) | 82 (67) | 353 (60) | ||
| T2a | 142 (23) | 130 (22) | 33 (27) | 305 (23) | 39.0 (31) | 56 (19) | 33 (27) | 133 (24) | ||
| T2b | 53 (9) | 23 (4) | 8 (7) | 84 (6) | 15 (12) | 24 (8) | 8 (7) | 56 (10) | ||
| T2c | 39 (6) | 13 (2) | 0 (0) | 52 (4) | 18 (14) | 10 (3) | 0 (0) | 32 (6) | ||
| Gleason score | 0.0112 | <0.00123 | ||||||||
| ≤6 | 290 (46) | 370 (61) | 71 (58) | 731 (54) | 42 (34) | 130 (44) | 99 (73) | 271 (50) | ||
| 7 | 280 (45) | 207 (34) | 48 (39) | 535 (40) | 61 (49) | 122 (42) | 32 (24) | 215 (39) | ||
| ≥8 | 57 (9) | 26 (4) | 3 (3) | 86 (6) | 22 (18) | 42 (14) | 3 (8) | 67 (12) | ||
| Risk group | 0.01123 | <0.00112 | ||||||||
| Low | 191 (31) | 322 (53) | 51 (42) | 564 (42) | 26 (21) | 100 (34) | 73 (54) | 199 (36) | ||
| Intermediate | 354 (57) | 246 (41) | 68 (55) | 668 (49) | 65 (52) | 139 (47) | 52 (38) | 256 (46) | ||
| High | 82 (13) | 35 (6) | 4 (3) | 121 (9) | 35 (28) | 54 (18) | 11 (8) | 100 (18) | ||
1
Norway vs USA
2
Norway vs Spain
3
USA vs Spain