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. 2016 Sep 13;354:i4694. doi: 10.1136/bmj.i4694

Table 2.

Characteristics of included studies that used 50 g oral glucose challenge test (OGCT) or 100 g oral glucose tolerance test (OGTT) for diagnosis of gestational diabetes

No of women Test type Test timing* Diagnosis exclusion criteria (mmol/L) Outcomes†
F 1 2 LGA Macrosomia S dystocia Neonatal hypoglyc Pre-eclampsia/PIH Preterm birth C section Ind labour Ins delivery
Carr,25 2011, US (Seattle) 25 969 50 g OGCT X 100 g OGTT ≥2 values fasting ≥5.3, 1 hour ≥10.0, 2 hour ≥8.6, and 3 hour ≥7.8 X X
Chandna,26 2006, Pakistan (Karachi) 633 50 g OGCT X NR X X X X
Cheng,27 2007, US (California) 13 901 50 g OGCT X NR X X X X X
Figueroa,28 2013, US (multicentre) 1839 50 g OGCT X 100 g OGTT fasting <5.3 + ≥2 values: 1 hour ≥10.0, 2 hour ≥8.6, 3 hour ≥7.8 X X X
Hillier,29 2008, US (Hawaii and Portland) 41 450 50 g OGCT X 100 g OGTT Two criteria used: (i) ≥2 values: fasting ≥5.8 or 1 hour ≥10.5 or 2 hour ≥9.2 or 3 hour ≥8.0; (ii) ≥2 values: fasting ≥5.3 or 1 hour ≥10.0 or 2 hour ≥8.6 or 3 hour ≥7.8 X  —
Ong,30 2008, UK (Cambridge) 3826 50 g OGCT X 50 g OGCT 1-hr >7.8 and 75 g OGTT levels NR. Fasting >6.1 2 hour level NR X X
Scholl,31 2001, US (New Jersey) 1157 50 g OGCT X NR X X X X
Sermer,32 1995, Canada (Toronto) 3637 50 g OGCT / 100 g OGTT X X X 100 g OGTT ≥2 values: fasting >5.8 or 1 hour >10.5 or 2 hour >9.1 or 3 hour >8.0 X X X
Witter,33 1988, US (Baltimore) 3897 50 g OGCT X 100 g OGTT ≥2 values: fasting ≥5.8 or 1 hour ≥10.5 or 2 hour >9.1 or 3 hour >8.0 X
Yee,34 2011, US (California) 13 789 50 g OGCT X 100 g OGTT ≥2 values: fasting >5.8 or 1 hour ≥10.5 or 2 hour ≥9.1 or 3 hour ≥8.0 X X X X X

LGA=large for gestational age; NR=not reported.

*F=fasting, 1=one hour post-load, 2=two hours post-load.

†Large for gestational age, macrosomia, shoulder dystocia, neonatal hypoglycaemia, pre-eclampsia/PIH (pregnancy induced hypertension), preterm birth, caesarean section, induced labour, instrumental delivery.