Table 3.
Characteristics of included studies that used 75 g oral glucose tolerance test (OGTT) for diagnosis of gestational diabetes
| No of women | Test timing* | Diagnosis exclusion criteria (mmol/L) | Outcomes† | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| F | 1 | 2 | LGA | Macrosomia | Sh dystocia | Neonatal hypogly | Pre-eclampsia/PIH | Preterm birth | C section | Ind labour | Ins delivery | |||
| Aris,35 2014, Singapore | 1081 | X | — | X | 75 g OGTT fasting ≥7.0 or 2 hour ≥7.8 | X | — | — | — | — | — | — | — | — |
| Atlantic Dip, 2015, Ireland (west coast) | 4869 | X | — | X | 75 g OGTT fasting ≥6.1 or 2 hour ≥7.8 | X | X | X | — | X | X | X | — | X |
| BIB, 2015, UK (Bradford) | 9645 | X | — | X | 75 g OGTT fasting ≥6.1 or 2 hour ≥7.8 | X | X | X | — | X | X | X | X | X |
| HAPO group,8 2008, international multicentre | 23 316 | X | X | X | 75 g OGTT fasting > 5.8 or 2 hour >11.1 or RPG >8.9 | X | — | — | X | — | — | X | — | — |
| HAPO group,36 2010, international multicentre | 21 364 | X | X | X | 75 g OGTT fasting >5.8 or 2 hour >11.1 or RPG >8.9 | — | — | — | — | X | — | — | — | — |
| Jensen,37 2001, Denmark (multicentre) | 2904 | X | — | X | 75 g OGTT ≥2 values: fasting >5.7 or 30 mins >11.9 or 1 hour 12.0 or 90 mins >9.7 or 2 hour >8.9 or 180 mins >7.4 | X | X | X | X | X | X | X | X | X |
| Kerenyi,38 2009, Hungary (Budapest) | 3787 | X | — | X | 75 g OGTT fasting ≥7.0 or 2 hour ≥7.8 | X | — | — | — | — | — | — | — | — |
| Lao,39 2003, China (Hong Kong), | 2168 | — | — | X | 75 g OGTT 2 hour ≥8.0 | X | X | — | — | — | X | X | — | — |
| Metzger,40 [HAPO] 2010 International multicentre | 17 094 | X | X | X | 75 g OGTT fasting >5.8 or 2 hour >11.1 or RPG >8.9 | — | — | — | X | — | — | — | — | — |
| Moses,41 1995, Australia (Illawarra, NSW) | 1441 | — | — | X | 75g OGTT 2 hour ≥8.0 | X | — | — | — | — | — | X | — | X |
| Pettitt,42 1980, US (Arizona) | 811 | — | — | X | 75g OGTT 2 hour ≥11.1 | X | — | — | — | — | X | X | — | — |
| Savona-Ventura,43 2010, Malta | 1289 | X | — | X | NR | — | X | — | — | X | — | — | — | — |
NR=not reported; RPG=random plasma glucose.
*F=fasting, 1=one hour post-load, 2=two hours post-load.
†Large for gestational age, macrosomia, shoulder dystocia, neonatal hypoglycaemia, pre-eclampsia/PIH (pregnancy induced hypertension), preterm birth, caesarean section, induced labour, instrumental delivery.